About the Authors

Marcel Wolbers

mwolbers@oucru.org

Affiliations Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland, Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Program, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Abdel Babiker

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Caroline Sabin

Affiliation University College London Medical School, London, United Kingdom

Jim Young

Affiliation Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland

Maria Dorrucci

Affiliation Istituto Superiore di Sanità, Rome, Italy

Geneviève Chêne

Affiliation Université Bordeaux II, Bordeaux, France

Cristina Mussini

Affiliation University of Modena and Reggio Emilia and Azienda Policlinico, Modena, Italy

Kholoud Porter

Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

Heiner C. Bucher

Affiliation Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland

on behalf of the CASCADE Collaboration

Membership of the CASCADE Collaboration is provided in the Acknowledgments.

Competing Interests

HCB received travel grants, honoraria, and unrestricted research grants from various pharmaceutical companies including, GlaxoSmithKline, Bristol-Myers-Squibb, Gilead, Roche, Abbott, Tibotec, and Boehringer-Ingelheim. The research of MW, JY, and HCB is supported by unrestricted grants from santésuisse and the Gottfried and Julia Bangerter-Rhyner-Foundation. The Medical Research Council, Clinical Trials HIV Group, led by AB, received donated drugs and/or financial support for substudies from the following pharmaceutical companies: Abbott, Boehringer Ingelheim, Bristol-Myers Squibb, Cipla, Gilead, Tibotec, Roche, GlaxoSmithKline, Indevus, Merck, Novartis, Sanofi Pasteur, and Virco. KP also received honorarium from Tibotec. CS has received funding for research, teaching, and consultancy from several pharmaceutical companies (GlaxoSmithKline, Gilead Sciences, Bristol-Myers Squibb, and Tibotec) over the last few years. CM received travel grants and honoraria from: GlaxoSmithKline, Bristol-Myers-Squibb, Gilead, Roche, Abbott, Tibotec, and Boehringer-Ingelheim. The research of CM is supported by Istituto Superiore di Sanità.

Author Contributions

ICMJE criteria for authorship read and met: MW AB CS JY MD GC CM KP HCB. Agree with the manuscript's results and conclusions: MW AB CS JY MD GC CM KP HCB. Designed the experiments/the study: MW AB KP HCB. Analyzed the data: MW. Collected data/did experiments for the study: CS MD GC KP HCB. Enrolled patients: MD. Wrote the first draft of the paper: MW. Contributed to the writing of the paper: AB CS JY MD GC CM KP HCB. MW had full access to all data in the study and had final responsibility for the decision to submit this report for publication. Secured funding for the study: KP. Obtained funding for the project: HCB.