Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study

Evelyne Decullier; An-Wen Chan; François Chapuis

doi:10.1371/journal.pmed.1000034

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Peer-reviewed

Research Article

Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study

Evelyne Decullier,

Affiliations Hospices Civils de Lyon, Pôle Information Médicale et Evaluation en Recherche, Lyon, France , Université de Lyon, Laboratoire Santé Individu Société (EA SIS), Lyon, France , Université Lyon 1, Lyon, France , Comité de Protection des Personnes, CPP Sud-Est III, Lyon, France
⨯
An-Wen Chan,

Affiliation Mayo Clinic, Rochester, Minnesota, United States
⨯
François Chapuis

*To whom correspondence should be addressed. E-mail: francois.chapuis@chu-lyon.fr

Affiliations Hospices Civils de Lyon, Pôle Information Médicale et Evaluation en Recherche, Lyon, France , Université de Lyon, Laboratoire Santé Individu Société (EA SIS), Lyon, France , Comité de Protection des Personnes, CPP Sud-Est III, Lyon, France , Université Lyon 1, Réseau d'Épidémiologie Clinique International Francophone (RECIF), Lyon, France
⨯

Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study

Evelyne Decullier,
An-Wen Chan,
François Chapuis

Published: February 17, 2009
https://doi.org/10.1371/journal.pmed.1000034

About the Authors

Evelyne Decullier

Affiliations Hospices Civils de Lyon, Pôle Information Médicale et Evaluation en Recherche, Lyon, France , Université de Lyon, Laboratoire Santé Individu Société (EA SIS), Lyon, France , Université Lyon 1, Lyon, France , Comité de Protection des Personnes, CPP Sud-Est III, Lyon, France

An-Wen Chan

Affiliation Mayo Clinic, Rochester, Minnesota, United States

François Chapuis

*To whom correspondence should be addressed. E-mail: francois.chapuis@chu-lyon.fr

Affiliations Hospices Civils de Lyon, Pôle Information Médicale et Evaluation en Recherche, Lyon, France , Université de Lyon, Laboratoire Santé Individu Société (EA SIS), Lyon, France , Comité de Protection des Personnes, CPP Sud-Est III, Lyon, France , Université Lyon 1, Réseau d'Épidémiologie Clinique International Francophone (RECIF), Lyon, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ED and FC conceived and designed the experiments. ED, A-WC, and FC analyzed the data. ED, A-WC, and FC wrote the paper.

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Phase I clinical investigation
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Phase III clinical investigation
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Drug research and development
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Phase II clinical investigation
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Clinical trials
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Questionnaires
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Publication ethics
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Phase IV clinical investigation
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