About the Authors

George Davey Smith

To whom correspondence should be addressed. E-mail: george.davey-smith@bristol.ac.uk

Affiliations Department of Social Medicine, University of Bristol, Bristol, United Kingdom , Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom

Debbie A Lawlor

Affiliations Department of Social Medicine, University of Bristol, Bristol, United Kingdom , Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom

Roger Harbord

Affiliation Department of Social Medicine, University of Bristol, Bristol, United Kingdom

Nic Timpson

Affiliations Department of Social Medicine, University of Bristol, Bristol, United Kingdom , Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom

Ian Day

Affiliations Department of Social Medicine, University of Bristol, Bristol, United Kingdom , Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom

Shah Ebrahim

Affiliation Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

GDS, SE, and ID designed the study. DAL and RH analyzed the data. DAL and SE enrolled patients. GDS, DAL, RH, NT, ID, and SE contributed to writing the paper.