Detection of Intracellular Bacterial Communities in Human Urinary Tract Infection

David A Rosen; Thomas M Hooton; Walter E Stamm; Peter A Humphrey; Scott J Hultgren

doi:10.1371/journal.pmed.0040329

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Open Access

Peer-reviewed

Research Article

Detection of Intracellular Bacterial Communities in Human Urinary Tract Infection

David A Rosen,

Affiliation Department of Molecular Microbiology and Microbial Pathogenesis, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Thomas M Hooton,

Affiliation Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Walter E Stamm,

Affiliation Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Peter A Humphrey,

Affiliation Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Scott J Hultgren

Affiliation Department of Molecular Microbiology and Microbial Pathogenesis, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯

Detection of Intracellular Bacterial Communities in Human Urinary Tract Infection

David A Rosen,
Thomas M Hooton,
Walter E Stamm,
Peter A Humphrey,
Scott J Hultgren

Published: December 18, 2007
https://doi.org/10.1371/journal.pmed.0040329

About the Authors

David A Rosen: Affiliation Department of Molecular Microbiology and Microbial Pathogenesis, Washington University School of Medicine, St. Louis, Missouri, United States of America
Thomas M Hooton: Affiliation Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America
Walter E Stamm: Affiliation Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America
Peter A Humphrey: Affiliation Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
Scott J Hultgren: Affiliation Department of Molecular Microbiology and Microbial Pathogenesis, Washington University School of Medicine, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DAR, TMH, WES, and SJH designed the study. TMH and WES enrolled patients. DAR, PAH, and SJH designed and performed the experiments. DAR, TMH, WES, PAH, and SJH analyzed the data and contributed to writing and editing the paper.

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Urine
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Cystitis
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Bladder
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Bacteria
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Intracellular pathogens
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Urinary tract infections
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Bacterial pathogens
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Light microscopy
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