About the Authors
- Kay L Pogue-Geile
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Contributed equally to this work with: Kay L Pogue-Geile, Ru Chen
¤ Current address: Division of Pathology, National Surgical Breast and Bowel Project, Pittsburgh, Pennsylvania, United States of America
Affiliation Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
- Ru Chen
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Contributed equally to this work with: Kay L Pogue-Geile, Ru Chen
Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America
- Mary P Bronner
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Affiliation Department of Pathology, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America
- Tatjana Crnogorac-Jurcevic
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Affiliation Molecular Oncology Unit, Cancer Research United Kingdom, Barts and the London School of Medicine and Dentistry, London, United Kingdom
- Kara White Moyes
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Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America
- Sally Dowen
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Affiliation Molecular Oncology Unit, Cancer Research United Kingdom, Barts and the London School of Medicine and Dentistry, London, United Kingdom
- Carol A Otey
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Affiliation Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, North Carolina, United States of America
- David A Crispin
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Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America
- Ryan D George
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Affiliation Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
- David C Whitcomb
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Affiliations Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America , Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America , Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
- Teresa A Brentnall
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*To whom correspondence should be addressed. E-mail: teribr@u.washington.edu
Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America
Competing Interests
TAB is in the process of filing a patent for the use of palladin as a marker for pancreatic cancer; KLPG, RC, DCW are participants in the same patent application.
Author Contributions
KLPG, RC, MPB, TCJ, CAO, DAC, DCW, and TAB designed the study. KLPG, RC, MPB, KWM, CAO, DAC, DCW, and TAB analyzed the data. MPB and TAB enrolled patients. KLPG, RC, MPB, KW, CAO, DAC, DCW, and TAB contributed to writing the paper. TAB, KWM, KLPG, RC, MPB, SD, and DAC collected data or did experiments for the study. KWM and RC performed PCR and sequence analysis of candidate genes, plasmid construction and HeLa cell culture and transfections. KLPG and RDG printed the microarray, hybridized RNA from pancreatic tissue samples to the customized microarray, and collected data.