Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges

Roland R Regoes; Ira M Longini Jr; Mark B Feinberg; Silvija I Staprans

doi:10.1371/journal.pmed.0020249

Loading metrics

Open Access

Peer-reviewed

Research Article

Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges

Roland R Regoes ,

*To whom correspondence should be addressed. E-mail: rregoes@emory.edu

Affiliation Department of Biology, Emory University, Atlanta, Georgia, United States of America
⨯
Ira M Longini Jr,

Affiliation Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America
⨯
Mark B Feinberg,

Affiliations Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America, Merck Vaccine Division, Merck, West Point, Pennsylvania, United States of America
⨯
Silvija I Staprans

Affiliation Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America
⨯

Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges

Roland R Regoes,
Ira M Longini Jr,
Mark B Feinberg,
Silvija I Staprans

Published: July 19, 2005
https://doi.org/10.1371/journal.pmed.0020249

About the Authors

Roland R Regoes

*To whom correspondence should be addressed. E-mail: rregoes@emory.edu

Affiliation Department of Biology, Emory University, Atlanta, Georgia, United States of America

Ira M Longini Jr

Affiliation Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

Mark B Feinberg

Affiliations Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America, Merck Vaccine Division, Merck, West Point, Pennsylvania, United States of America

Silvija I Staprans

Affiliation Departments of Medicine and Microbiology and Immunology, Emory University School of Medicine and the Emory Vaccine Center, Atlanta, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RRR performed the analysis. RRR, IML, MBF, and SIS designed the study and wrote the paper.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

HIV vaccines
Is the Subject Area "HIV vaccines" applicable to this article?

Thanks for your feedback.
Vaccine development
Is the Subject Area "Vaccine development" applicable to this article?

Thanks for your feedback.
Preventive medicine
Is the Subject Area "Preventive medicine" applicable to this article?

Thanks for your feedback.
Vaccines
Is the Subject Area "Vaccines" applicable to this article?

Thanks for your feedback.
Experimental design
Is the Subject Area "Experimental design" applicable to this article?

Thanks for your feedback.
Viral vaccines
Is the Subject Area "Viral vaccines" applicable to this article?

Thanks for your feedback.
Vaccination and immunization
Is the Subject Area "Vaccination and immunization" applicable to this article?

Thanks for your feedback.
HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.