March 2, 2026
Image credit: Megan Clark, Unsplash
03/17/2026
Research Article
In this metabolomics study, Yulu Zheng and colleagues investigate associations between microbial metabolites and coronary heart disease, performing discovery and validation analyses using five different cohorts.
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Browse Issues 2004 – 2026
03/12/2026
Research Article
Elliott W Sharp and colleagues develop Large Language Model-Based Methodology to quantify unmet needs among human diseases considering factors related to patient suffering, standard of care, and accessibility of care.
Image credit: BrianPenny, Pixabay
03/03/2026
Perspective
Global health architecture as we know it is at a structural inflection point. In this Perspective, Ebere Okereke discusses priorities for sustainable progress, including restoring country agency, strengthening national institutions, and securing predictable, sustainable health financing.
Image credit: Mikhail Nilov, Pexels
03/13/2026
Perspective
In this Perspective, George Davey Smith and colleagues outline how and why gene-environment equivalence, the fundamental principle of Mendelian Randomization (MR), must be properly applied and critically considered in MR studies.
Image credit: qimono, Pixabay
03/12/2026
Research Article
In a case-crossover study, Heather McBrien and colleagues investigate if power outages are associated with cardiovascular and respiratory hospitalizations in older adults in the US.
Image credit: Anne Nygård, Unsplash
03/05/2026
Research Article
Using national registry data, Christina-Evmorfia Kampitsi and colleagues examine patterns in childhood cancer incidence and survival before and during the COVID-19 pandemic in Sweden.
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03/10/2026
Perspective
David Page and colleagues discuss how spatially profiling immune-tumor cell interactions may help predict outcomes in early-stage breast cancer.
Image credit: National Cancer Institute, Unsplash
03/06/2026
Research Article
Shih-Chieh Shao and colleagues investigate the risk of hypomagnesemia in type 2 diabetes treated with SGLT2 inhibitors, GLP-1 RAs, and DPP4 inhibitors.
Image credit: Mary Borozdina, Unsplash
03/02/2026
Research Article
By Richard A Armstrong and colleagues.
Image credit: geralt, Pixabay
02/17/2026
Research Article
By Yanling Deng and colleagues.
Image credit: Mike Marrah, unsplash
In this Perspective article, Ann Weber and Gary Darmstadt discuss how benchmarking life expectancy against what is achievable reveals how sex disadvantage shifts by age, place, and time, and reframes inequality as unrealized potential due to social and structural constraints rather than differences in biology.
In this Editorial, Guest Editors Timothy R. Walsh, Ana C. Gales, Ramanan Laxminarayan, and our PLOS Medicine Editor Philippa C. Dodd discuss the Special Issue dedicated to Antimicrobial resistance and emphasize the urgent threat of AMR.
Ruchita Balasubramanian and colleagues, estimate the incidence of hospital-associated infections resistant to antibiotics in 195 countries using point prevalence survey data.
James Neal Russell and colleagues explore antibiotic use and mortality prediction in hospitalised neonates and infants with sepsis.
Silvia Bertagnolio, Amitabh Bipin Suthar, Olga Tosas and Kitty Van Weezenbeek discuss surveillance of antimicrobial resistance, the existing limitations and the implications this has on accurate determination of incidence.
In this Special Issue, we present a fascinating array of research papers providing insights into various facets of mental health during the pandemic.
This collection of research articles highlights the multi-faceted challenges imposed by drug-resistant bacteria, the consequences for health and economics, and interventions that could lessen the burden.
In this Collection, PLOS Medicine presents high-quality translational research and clinical studies on advances in early cancer detection.
This Special Issue brings together the latest research on child and adolescent health, including strategies to monitor and combat child mortality from birth through adolescence, and environmental impacts on child health and mortality.
This 2019 Special Issue highlights the importance of nutrition for maternal and child health.
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