Cover
A depiction of a reconstructed HSN neuron from the fly rendered with ray-tracing program POV-Ray.
In "Ceci n'est pas une pipe," René Magritte faithfully depicts a pipe but all the same proclaims that it isn't a pipe: it is a painting of a pipe. We allude to Magritte's painting here, showing that by rebuilding a neuron's anatomy, we create something that is not a neuron: it is the model of a neuron (see Cuntz et al., doi:10.1371/journal.pcbi.1000251).
Image Credit: Hermann Cuntz (University College London).
Perspective
I Am Not a Scientist, I Am a Number
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000247
Research Articles
Spontaneous Reaction Silencing in Metabolic Optimization
PLOS Computational Biology: published December 5, 2008 | https://doi.org/10.1371/journal.pcbi.1000236
Formation and Growth of Oligomers: A Monte Carlo Study of an Amyloid Tau Fragment
PLOS Computational Biology: published December 5, 2008 | https://doi.org/10.1371/journal.pcbi.1000238
Encoding of Naturalistic Stimuli by Local Field Potential Spectra in Networks of Excitatory and Inhibitory Neurons
PLOS Computational Biology: published December 12, 2008 | https://doi.org/10.1371/journal.pcbi.1000239
Dynamic Correlation between Intrahost HIV-1 Quasispecies Evolution and Disease Progression
PLOS Computational Biology: published December 12, 2008 | https://doi.org/10.1371/journal.pcbi.1000240
Disordered Flanks Prevent Peptide Aggregation
PLOS Computational Biology: published December 19, 2008 | https://doi.org/10.1371/journal.pcbi.1000241
Dependence of Bacterial Chemotaxis on Gradient Shape and Adaptation Rate
PLOS Computational Biology: published December 19, 2008 | https://doi.org/10.1371/journal.pcbi.1000242
Malleable Machines in Transcription Regulation: The Mediator Complex
PLOS Computational Biology: published December 19, 2008 | https://doi.org/10.1371/journal.pcbi.1000243
Association Rate Constants of Ras-Effector Interactions Are Evolutionarily Conserved
PLOS Computational Biology: published December 19, 2008 | https://doi.org/10.1371/journal.pcbi.1000245
Mechanics and Dynamics of X-Chromosome Pairing at X Inactivation
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000244
A Mathematical Framework for the Selection of an Optimal Set of Peptides for Epitope-Based Vaccines
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000246
Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000248
Search Algorithms as a Framework for the Optimization of Drug Combinations
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000249
Identification of Mechanosensitive Genes during Embryonic Bone Formation
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000250
The Morphological Identity of Insect Dendrites
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000251
A Common Cortical Circuit Mechanism for Perceptual Categorical Discrimination and Veridical Judgment
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000253
Game Theory of Mind
PLOS Computational Biology: published December 26, 2008 | https://doi.org/10.1371/journal.pcbi.1000254