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Correction: A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

  • Christian Quirouette,
  • Nada P. Younis,
  • Micaela B. Reddy,
  • Catherine A. A. Beauchemin

In Fig 3 there is an error in the text in the legend within the figure for parts d, e, f. It says 1 dpi, 2 dpi, 3 dpi, 4 dpi, 7 dpi, 7 dpi, but it should say 0 dpi, 1 dpi, 2 dpi, 3 dpi, 4 dpi, 7 dpi. The authors have provided a corrected version here.

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Fig 3. IAV infection kinetics in the presence of diffusion and advection.

(a,b,c) Time course (averaged over space) of the infection for the fraction of cells in the (a) target/uninfected or (b) infectious state, and (c) the infectious virus concentration, obtained using the ODE MM (dashed) or the spatial MM (solid), as the rate of virus production, p, is varied. (d,e,f) Localized fraction of cells in the (d) target or (e) infectious state and (f) the infectious virus concentration as a function of depth within the HRT shown at specific days post-infection (dpi). (g,h,i) Same as (a,b,c) but varying the depth of deposition of the initial virus inoculum (xd). (j,k,l) Similar to (a,b,c) but rather than being averaged over space, the infection time course is shown at specific, spatially localized depths (x). Unless otherwise noted, p = 11 × pBaccam and xd = 15 cm.

https://doi.org/10.1371/journal.pcbi.1008424.g001

Reference

  1. 1. Quirouette C, Younis NP, Reddy MB, Beauchemin CAA (2020) A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract. PLoS Comput Biol 16(4): e1007705. https://doi.org/10.1371/journal.pcbi.1007705 pmid:32282797