Figures
Visualising topological features in red pulp cells of a healthy mouse spleen with PWDS
We introduce Persistence Weighted Death Simplices (PWDS), a visualisation of the topological features detected by persistent homology in 2D imaging data. Each triangle marks the approximate location of a loop in the cell distribution, with colour indicating whether the loop is formed by proximal (red) or distal (blue) cells, and intensity reflecting its prominence. This visualisation highlights the multiscale structure of cell arrangements and provides an interpretable link between topological features and biological tissue organisation. Torras-Pérez et al. 2025
Image Credit: Maria Torras-Pérez et al.
Citation: (2025) PLoS Computational Biology Issue Image | Vol. 21(10) November 2025. PLoS Comput Biol 21(10): ev21.i10. https://doi.org/10.1371/image.pcbi.v21.i10
Published: November 11, 2025
Copyright: © 2025 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We introduce Persistence Weighted Death Simplices (PWDS), a visualisation of the topological features detected by persistent homology in 2D imaging data. Each triangle marks the approximate location of a loop in the cell distribution, with colour indicating whether the loop is formed by proximal (red) or distal (blue) cells, and intensity reflecting its prominence. This visualisation highlights the multiscale structure of cell arrangements and provides an interpretable link between topological features and biological tissue organisation. Torras-Pérez et al. 2025
Image Credit: Maria Torras-Pérez et al.