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PLoS Computational Biology Issue Image | Vol. 20(8) September 2024

Working model for START transition via SBF activation

The figure illustrates the core model of SBF activation and inactivation by Clns and Clbs, focusing on key interactions in the budding yeast start transition (START-BYCC). It highlights components such as Swi4, Swi6, Whi5, kinases (Cln3, Cln1,2, Clb5,6, Clb1,2), and the export protein Msn5, with color-coded elements representing various states of activity. Activating and inactivating phosphorylations are shown by white and black-filled circles, respectively. The nucleus and cytoplasm are distinguished by blue-gray and white backgrounds. Detailed descriptions of abundance, regulation, and localization are provided in the companion article and supplementary material. Ravi et al, 2024

Image Credit: Janani Ravi

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Working model for START transition via SBF activation

The figure illustrates the core model of SBF activation and inactivation by Clns and Clbs, focusing on key interactions in the budding yeast start transition (START-BYCC). It highlights components such as Swi4, Swi6, Whi5, kinases (Cln3, Cln1,2, Clb5,6, Clb1,2), and the export protein Msn5, with color-coded elements representing various states of activity. Activating and inactivating phosphorylations are shown by white and black-filled circles, respectively. The nucleus and cytoplasm are distinguished by blue-gray and white backgrounds. Detailed descriptions of abundance, regulation, and localization are provided in the companion article and supplementary material. Ravi et al, 2024

Image Credit: Janani Ravi

https://doi.org/10.1371/image.pcbi.v20.i08.g001