Figures
Standardizing non-ribosomal peptide synthetase assembly line by conserved motifs
The cat (C-A-T) on the image represents the condensation (C), adenylation (A), and thiolation (T) domains that constitute the basic module of the non-ribosomal peptide synthetase (NRPS). Each module selects a specific substrate, represented by the ball on the cat’s head, and the train of cats represents the NRPS assembly line. The peptide product of NRPS (a string of balls) is placed on the right. The standardized architecture with conserved motifs was displayed as a ruler around the assembly line. In our publication, standardization of NRPS is achieved by NRPS Motif Finder. He et al. 2023
Image Credit: Rezin Ghost
Citation: (2023) PLoS Computational Biology Issue Image | Vol. 19(5) June 2023. PLoS Comput Biol 19(5): ev19.i05. https://doi.org/10.1371/image.pcbi.v19.i05
Published: June 2, 2023
Copyright: © 2023 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The cat (C-A-T) on the image represents the condensation (C), adenylation (A), and thiolation (T) domains that constitute the basic module of the non-ribosomal peptide synthetase (NRPS). Each module selects a specific substrate, represented by the ball on the cat’s head, and the train of cats represents the NRPS assembly line. The peptide product of NRPS (a string of balls) is placed on the right. The standardized architecture with conserved motifs was displayed as a ruler around the assembly line. In our publication, standardization of NRPS is achieved by NRPS Motif Finder. He et al. 2023
Image Credit: Rezin Ghost