Figures
In silico irradiation of Hi-C genome conformation
The in silico proton irradiation of 3D genome structure derived from Hi-C geometry. The track-structure of the primary protons (red) traversing through the IMR90 cell nucleus, producing secondary electrons (green) as they travel, the energy depositions of these particles damage the DNA. This damage to the DNA is then scored as single- or double-stranded breaks and the distribution of these are analysed. Ingram et al.
Image Credit: Samuel P Ingram Nicholas T Henthorn
Citation: (2021) PLoS Computational Biology Issue Image | Vol. 16(12) January 2021. PLoS Comput Biol 16(12): ev16.i12. https://doi.org/10.1371/image.pcbi.v16.i12
Published: January 4, 2021
Copyright: © 2021 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The in silico proton irradiation of 3D genome structure derived from Hi-C geometry. The track-structure of the primary protons (red) traversing through the IMR90 cell nucleus, producing secondary electrons (green) as they travel, the energy depositions of these particles damage the DNA. This damage to the DNA is then scored as single- or double-stranded breaks and the distribution of these are analysed. Ingram et al.
Image Credit: Samuel P Ingram Nicholas T Henthorn