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PLoS Computational Biology Issue Image | Vol. 11(4) April 2015

The role of inhibition in a computational model of an auditory cortical neuron during the encoding of temporal information.

Using single-unit recordings from awake marmosets (Callithrix jacchus), we validate several model predictions, including differences in the temporal fidelity, discharge rates and temporal dynamics of stimulus-evoked responses between neurons with rate and temporal representations. Together these data suggest that feedforward inhibition provides a parsimonious explanation of the neural coding dichotomy observed in auditory cortex. Bendor.

Image Credit: Daniel Bendor

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The role of inhibition in a computational model of an auditory cortical neuron during the encoding of temporal information.

Using single-unit recordings from awake marmosets (Callithrix jacchus), we validate several model predictions, including differences in the temporal fidelity, discharge rates and temporal dynamics of stimulus-evoked responses between neurons with rate and temporal representations. Together these data suggest that feedforward inhibition provides a parsimonious explanation of the neural coding dichotomy observed in auditory cortex. Bendor.

Image Credit: Daniel Bendor

https://doi.org/10.1371/image.pcbi.v11.i04.g001