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PLoS Computational Biology Issue Image | Vol. 9(10) October 2013

The ligand clouds concept: A scenario of ligand binding with intrinsically disordered proteins

The ligand (purple dots) binds to intrinsically disordered protein (c-Myc) at different sites along the chain and behaves like "ligand clouds" (purple clouds). See Jin et al.

Image Credit: Fan Jin, Luhua Lai, and Zhirong Liu (College of Chemistry and Molecular Engineering, Peking University, China).

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The ligand clouds concept: A scenario of ligand binding with intrinsically disordered proteins

The ligand (purple dots) binds to intrinsically disordered protein (c-Myc) at different sites along the chain and behaves like "ligand clouds" (purple clouds). See Jin et al.

Image Credit: Fan Jin, Luhua Lai, and Zhirong Liu (College of Chemistry and Molecular Engineering, Peking University, China).

https://doi.org/10.1371/image.pcbi.v09.i10.g001