Figures
Stem cells in small intestinal crypts
Fluorescently stained wholemount of mouse small intestine. A single confocal optical section at the base of the crypts is stained to show nuclei (blue), F-actin (red), and intestinal stem cells (green). Actin-rich smooth muscle fibres forming the muscular mucosae appear as a meshwork around the crypt bases. Lgr5 positive stem cells labelled with green fluorescent protein are found only in the crypt bases. See Dunn, et al. (10.1371/journal.pcbi.1002515).
Image Credit: Paul Appleton, College of Life Sciences, University of Dundee.
Citation: (2012) PLoS Computational Biology Issue Image | Vol. 8(5) May 2012. PLoS Comput Biol 8(5): ev08.i05. https://doi.org/10.1371/image.pcbi.v08.i05
Published: May 31, 2012
Copyright: © 2012 Appleton. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fluorescently stained wholemount of mouse small intestine. A single confocal optical section at the base of the crypts is stained to show nuclei (blue), F-actin (red), and intestinal stem cells (green). Actin-rich smooth muscle fibres forming the muscular mucosae appear as a meshwork around the crypt bases. Lgr5 positive stem cells labelled with green fluorescent protein are found only in the crypt bases. See Dunn, et al. (10.1371/journal.pcbi.1002515).
Image Credit: Paul Appleton, College of Life Sciences, University of Dundee.