Figures
Cloud topology in the yeast protein interaction network.
This figure represents the protein-protein interaction network topology of budding yeast. The outermost circle shows proteins with smaller numbers of interactions (gray dots) and proteins that interact with these are located on inner circles. Most large hubs are placed here (blue dots). Inner circles are dominated by medium size hubs (red dots) that are extensively connected to each other. This topology is mathematically similar to the router-level topology of the internet and represents networks according to highly optimized tolerance (see Hase et al., doi:10.1371/journal.pcbi.1000550).
Image Credit: Hiroaki Kitano and Takeshi Hase
Citation: (2009) PLoS Computational Biology Issue Image | Vol. 5(10) October 2009. PLoS Comput Biol 5(10): ev05.i10. https://doi.org/10.1371/image.pcbi.v05.i10
Published: October 30, 2009
Copyright: © 2009 Hase et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This figure represents the protein-protein interaction network topology of budding yeast. The outermost circle shows proteins with smaller numbers of interactions (gray dots) and proteins that interact with these are located on inner circles. Most large hubs are placed here (blue dots). Inner circles are dominated by medium size hubs (red dots) that are extensively connected to each other. This topology is mathematically similar to the router-level topology of the internet and represents networks according to highly optimized tolerance (see Hase et al., doi:10.1371/journal.pcbi.1000550).
Image Credit: Hiroaki Kitano and Takeshi Hase