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PLoS Computational Biology Issue Image | Vol. 3(3) March 2007

Location and nature of the differences between alternative splicing isoforms

Sequence changes introduced by alternative splicing and gene duplication are usually different. Shown here is the location and nature (using a hydrophobicity scale) of the differences between alternative splicing isoforms of MAPK9 (left), and between MAPK9 and the paralogs MAPK10 (center) and MAPK13 (right) (see Talavera et al).

Image Credit: Image created by David Talavera, Christine Vogel, and Xavier de la Cruz with PyMOL

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Location and nature of the differences between alternative splicing isoforms

Sequence changes introduced by alternative splicing and gene duplication are usually different. Shown here is the location and nature (using a hydrophobicity scale) of the differences between alternative splicing isoforms of MAPK9 (left), and between MAPK9 and the paralogs MAPK10 (center) and MAPK13 (right) (see Talavera et al).

Image Credit: Image created by David Talavera, Christine Vogel, and Xavier de la Cruz with PyMOL

https://doi.org/10.1371/image.pcbi.v03.i03.g001