Figures
Local fitness environments along an evolutionary path
The image depicts local fitness environments along an evolutionary path. The surfaces are based on measured data, and show the changes in fitness that can be achieved by a single base pair substitution. The first disc represents a duplicate repressor-operator pair, while the last represents a diverged pair. In this manner, a highly complex, multidimensional fitness landscape can be portrayed. The simulated paths explain why independent protein-DNA interactions can evolve rapidly (see Poelwijk et al).
Image Credit: Created by Frank Poelwijk and Daniel Kiviet using MATLAB, MOLMOL, and Jasc Paint Shop Pro.
Citation: (2006) PLoS Computational Biology Issue Image | Vol. 2(5) May 2006. PLoS Comput Biol 2(5): ev02.i05. https://doi.org/10.1371/image.pcbi.v02.i05
Published: May 26, 2006
Copyright: © 2006 Poelwijk et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The image depicts local fitness environments along an evolutionary path. The surfaces are based on measured data, and show the changes in fitness that can be achieved by a single base pair substitution. The first disc represents a duplicate repressor-operator pair, while the last represents a diverged pair. In this manner, a highly complex, multidimensional fitness landscape can be portrayed. The simulated paths explain why independent protein-DNA interactions can evolve rapidly (see Poelwijk et al).
Image Credit: Created by Frank Poelwijk and Daniel Kiviet using MATLAB, MOLMOL, and Jasc Paint Shop Pro.