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Table 1.

Categories of dual-use research in the life sciences warranting risk assessment, as previously identified by scientists and US policymakers [30], and corresponding emerging AI capabilities. Note that the emerging AI-enabled capabilities constitute an illustrative, not exhaustive, list.

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Fig 1.

Biosecurity evaluation development should follow a distinct process.

This figure is a simple schematic demonstrating that distinct evaluative methods will be needed for different types of biological AI models. Dual-use capabilities of concern should be translated into model type-specific evaluation methods that are linked to pre-specified thresholds and risk mitigation actions.

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