Fig 1.
COVID-19 hospital admissions and estimated cumulative infections for Travis County (Austin, TX) from March 1, 2020 to June 1, 2021.
(A) Daily reported COVID-19 hospital admissions per 1 million residents [50]. (B) Estimated cumulative infections with 95% credible intervals (black line and gray ribbon) compared to Texas statewide seroprevalence-based estimates (red points and error bars) [49].
Fig 2.
Estimated age-stratified COVID-19 burden in Travis country through June 1, 2021.
(A) Reported COVID-19 hospital admissions by age group. (B) Reported COVID-19 cases by age group. (C) Estimated percent infected by age group. (D) Estimated COVID-19 case reporting rates by age group up to June 1, 2021. In (A)-(D), horizontal dashed lines indicate county-wide average rates. (E) Estimated daily infection rates (line) and 95% credible intervals (ribbons) by age group. (F) Distribution of infections across age groups for each period of the epidemic. The spring period refers to the two-month time period before the first major wave from March 1, 2020 to May 1, 2020, the summer period refers to the two-month period containing the first major wave from June 1, 2020 to August 1, 2020, and the winter period refers to the two-month period containing the second major wave from December 1, 2020 until February 1, 2021. Bars indicate the fraction of all infections during the time period in each age group, with the error bars indicating the 95% credible intervals. The horizontal colored lines in panel F indicate the proportion of the Travis county population in the specified age group.
Table 1.
SARS-CoV-2 infection hospitalization rate (IHR) across Texas estimated from statewide seroprevalence and hospitalization data from July 29, 2020 through May 27, 2021.
Fig 3.
Reported and estimated COVID-19 burden by ZIP code for Travis County between March 1, 2020 and June 1, 2021.
(A) Reported COVID-19 cases per 100,000. (B) Reported COVID-19 hospitalizations per 100,000. (C) Social Vulnerability Index [14] (D) Estimated infection hospitalization rate (IHR). (E) Estimated cumulative infections as of June 1, 2021. (F) Estimated percent of COVID-19 infections that were reported. Thin black curves indicate Interstate 35 and highway US 183. The ZIP code map was based on TIGER/Line shapefiles provided by the US Census Bureau [56] accessed through the tidycensus R package for the year 2019 [57].
Fig 4.
Infection and reporting rates correlate with social vulnerability in Travis County from March 1, 2020 to June 1, 2021.
(A) Across the 46 ZIP codes, SVI is a significant predictor of estimated cumulative infections (p<0.001). The blue line and ribbon indicate the mean and 95% prediction interval from the fitted Poisson mixed-effects model. (B) Using the fitted model, we compare the expected infection rates among more and less vulnerable ZIP codes (specifically, ZIP codes at the 75th and 25th percentiles in the SVI distribution, respectively). The points indicate the expected ratio between these two values calculated using the estimated SVI regression coefficient from the 4-week time period; error bars indicate 95% CI’s. (C) Across the 46 ZIP codes, SVI is a significant predictor of estimated case reporting rates (p<0.001). The blue line and ribbon indicate the mean and 95% prediction interval from the fitted Poisson mixed-effects model. (D) Four week estimate for the inequality relationship between SVI and infection reporting rates across the 46 ZIP codes. Points and error bars show the mean and 95% CI for the relative reporting rate of individuals living in ZIP codes in the 75th SVI percentile compared with those living in the 25th SVI percentile. The red, horizontal dashed lines in B and D indicate if there were equitable infection risks or reporting rates across the 75th and 25th SVI percentile ZIP codes in the four week period. We overlay hospital admission time-series in B and D to showcase how inequality estimates compare with the progression of the local epidemic. For B and D we removed the ZIP codes reporting zero infections to stabilize the regression estimates.