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Fig 1.

Approach enforced in the EMULSION framework.

A generic simulation engine is coupled to a domain-specific modelling language (DSL), reinforcing interactions between modellers and scientists from other fields. Knowledge involved in epidemiological models is kept explicit, understandable and revisable as a structured text file. A few specific software add-ons can be written to complement the simulation engine if needed.

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Fig 2.

Structure of a transition between two states in state machines.

Individuals can be given a duration and actions when entering, staying in, or leaving the state. Transitions feature a rate, probability, or amount, and can be associated with actions performed on crossing, time-dependent ("calendar") conditions, or individual conditions restricting the capability to cross the transition, and escape conditions allowing individuals to leave their state before the nominal duration.

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Fig 3.

Diversity of modelling paradigms in EMULSION models.

EMULSION allows to represent within a same formalism (nested agents) several modelling paradigms, from the finest grained (individuals) to aggregations (compartments), including intermediary representations as a trade-off between computation time and preservation of individual details. The chosen modelling paradigm is associated with the appropriate combinations of agents.

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