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Table 1.

CNV detection methods on WGS data.

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Table 1 Expand

Table 2.

Formula to calculate TPR and FDR.

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Table 2 Expand

Fig 1.

Statistics of the detected CNVs.

(a) Detected CNV number. (b) Distribution of CNV size. (c) The Venn diagram of CNV detection methods.

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Fig 2.

The evaluation of sensitivity and specificity of CNV detection methods.

(a) TPR curves of the ten applications at sequencing depths from 5X to 50X. (b) FDR curves of the ten applications at sequencing depths from 5X to 50X.

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Fig 2 Expand

Fig 3.

The computational demands of the ten methods.

(a) Computation time as a function of sequencing depth from 5X to 50X. (b) Memory usage as a function of sequencing depth from 5X to 50X.

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Fig 3 Expand