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Fig 1.

Samples of IVUS-VH figures and segmented contour plots, smoothed contour plots.

Plots also include X-ray angiographic image and stacked segmented contours showing the 3D vessel geometry. Colors used in IVUS-VH: Red—necrotic core; White—dense calcium; Dark Green–Fibrous; Light Green—Fibro-Fatty.

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Fig 2.

Sketch explaining definitions of quarters, wall thickness, cap thickness, and lipid (lipid-rich necrotic core).

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Table 1.

The morphological features related indices classification: Cap index, Lipid index, Morphological index and comparison with AHA classifications [26, 3637].

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Table 1 Expand

Table 2.

The stress interval to assign the stress index and the distribution of the stress index.

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Table 2 Expand

Fig 3.

Samples plots of plaque wall stress, strain, wall shear stress and velocity on a mid-cut plane showing basic solution features.

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Fig 3 Expand

Fig 4.

Scatter plots of CPWS vs cap index, min cap thickness, lipid index, and morphological index.

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Table 3.

Correlation results between mechanical factors (CPWS/CPWSn, CFSS) and five morphological related factors (min cap thickness, cap index, lipid percentage, lipid index, and morphological index).

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Table 3 Expand

Table 4.

Correlation results between five morphological features (min cap thickness, cap index, lipid percentage, lipid index, and morphological index) and CPWS for each patient on patient level (p-values for no significance results used bold italic).

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Table 5.

Correlation results between stress index and five morphological related factors (min cap thickness, cap index, lipid percentage, lipid index, morphological index).

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Table 5 Expand

Table 6.

Agreement rates between stress index and cap index, lipid index and morphological index.

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