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Figure 1.

Idealized caricatures of virus phylogenies that show the effects of changes in viral population size.

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Figure 2.

Idealized caricatures of virus phylogenies that show the effects of population structure.

Red and blue circles represent spatial locations from which viral samples were isolated.

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Figure 3.

Idealized caricatures of virus phylogenies that show the effects of immune escape.

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Figure 4.

A gene genealogy illustrating internode intervals.

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Figure 5.

Phylogenetic tree of the HA1 region of the HA gene of influenza A (H3N2) from viruses sampled between 1968 and 2002.

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Table 1.

Estimated annual growth rates of Ne for early HIV sub-epidemics.

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Figure 6.

Between-host and within-host HIV phylogenies.

Sequences were downloaded from the LANL HIV sequence database (http://www.hiv.lanl.gov/content/sequence/HIV/SI_alignments/set1.html). Neighbor-joining trees were estimated from Alignment1, and the within host tree is based on data from patient 2. Trees were re-rooted using Path-o-gen using known sample dates (http://tree.bio.ed.ac.uk/software/pathogen/).

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