Figure 1.
Systemic view of the gene regulatory network model including relevant genes or transcription factors for Th1 Th2 cell differentiation.
Black edges depict positive regulation; red edges negative regulations.
Table 1.
The attractors of the boolean network modeling Th1/Th2 differentiation.
Table 2.
Number of attractors in knock-out networks.
Figure 2.
Number of attractors as the result of in silico knockout experiments, in the temporary stimulation activation modality.
Stacked bars represent the percentage of attractors expressing combinations of IL-4 and/or IFN-.
Figure 3.
Number of attractors as the result of in silico knockout experiments, in the persisting stimulation activation modality.
Stacked bars represent the percentage of attractors expressing combinations of IL-4 and/or IFN-.
Table 3.
Results of Pearson's correlation test of inhibitory gene pairs.
Table 4.
Specification rules for activation/inihibition links of the network in Figure 1.
Table 5.
Gene expression microarray datasets downloaded from the Gene Expression Omnibus repository.