Figure 1.
A Schematic Illustration of Head-to-Head Gene Organization
(A and B) Nonoverlapping and overlapping head-to-head gene pairs, respectively.
Figure 2.
Distribution of TSS Distance of Head-to-Head Genes
Table 1.
Distribution of Head-To-Head Gene Pairs on Each Chromosome
Figure 3.
Relationship between Head-to-Head Gene Pair Ratio and Gene Density
Table 2.
Conservation of Gene Pair Organization between Human and Fugu
Table 3.
Genomic Distances of Gene Pairs with Human-Fugu Linkage
Table 4.
Conservation of Gene Pair Organization between Human and Chicken
Table 5.
Genomic Distances of Gene Pairs with Human-Chicken Linkage
Table 6.
Average Genomic Distances of Gene Pairs with Human-Chicken-Fugu Linkage
Figure 4.
The Bimodal Distribution of the Expression Correlation between Head-to-Head Genes
h2h, correlation distribution for head-to-head gene pairs, averaged over three distributions derived from three microarray datasets separately; random, correlation distribution for random pairs, also averaged over three random distributions from three microarray datasets.
Figure 5.
The Distribution of Functional Similarities for Head-to-Head Gene Pairs
(A−C) GO subsystems “biological process,” “molecular function,” and “cellular component,” respectively.
Table 7.
Significant Cofunctions Associated with Head-To-Head Gene Pairs in the “Biological Process” (BP), “Molecular Function” (MF), and “Cellular Component” (CC) Subsystems
Table 8.
The Human Head-to-Head Gene Pairs Coding for Histone