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Figure 1.

Overlap of M. tuberculosis Growth-Essential Genes

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Table 1.

Number of LR5 Compound Binding Domains Predicted in the M. tuberculosis Growth-Essential Proteome

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Figure 2.

Box and Whisker Plots of GA-Optimized Weights from 100 Evolved Solutions

Each possible solution was able to rank eight of ten target genes within the top 25%.

M0, macrophage; n, number of experiments; nrp, nonreplicating persistence.

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Table 2.

Ranking of Persistence-Implied Genes with Only Latent-State Model Features

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Table 3.

Ranks of Studied Targets in Three Prioritized Lists

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Table 4.

Individual Features of Studied Targets

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Table 4.

Extended

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Table 5.

Weighting Schemes of Different Features Used to Prioritize TB Drug Targets

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