Multilabel prediction of virus target proteins via multimodal graph representation learning
Fig 5
Analysis of predicted and known VTPs in the human proteome across virus species.
(A) Distribution of predicted and known VTPs for each virus species. The results are classified into three categories: novel (newly predicted VTPs), recovered (overlap between predicted and known VTPs), and missing (known but unrecognized VTPs). (B) Distribution of GO terms enriched in predicted and known VTPs for each virus species. The results are classified into three categories: novel (terms enriched exclusively in predicted VTPs), recovered (overlapping terms between predicted and known VTPs), and missing (terms enriched exclusively in known VTPs). (C) Density map of proportion of H1N1 VTPs among the interacting neighbors of different samples. (D) Novel pathways related to H1N1 VTP candidates. (E) Interaction network of relevant VTPs in the adherens junction pathway. (F) Distribution of novel, recovered, and missing labels. The classification is similar to that of VTPs. (G) Network topology and evolutionary conservation attributes of SVTPs and MVTPs. SVTP: single virus target protein, and MVTP: multiple virus target protein. (H) Top 10 biological processes enriched in MVTPs.