A three-dimensional shear dependent continuum model of platelet aggregation under flow
Fig 8
3D rendering of numerically simulated clots and intrathrombus platelet species distributions.
Left column: shear rate of 300/s; right column: 1500/s. (A) Isovolume of subendothelial platelets (red) and bound unactivated platelets (green). (B) Same as in (A), with the addition of activated platelets bound via vWF (red). (C) Same as in (B), with an additional isovolume (blue) representing activated platelets bound via fibrinogen. Isovolumes are sliced along the channel centerline to enhance visualization. Together, these renderings illustrate how shear rate influences the spatial organization and composition of platelet populations within simulated thrombi.