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A three-dimensional shear dependent continuum model of platelet aggregation under flow

Fig 4

Shear-rate dependent functional forms of adhesion and cohesion.

Functional forms for the on-rates (left) and off-rates (right) used to extend shear dependence beyond 2000/s. Piecewise-linear functions were tested for both on- and off-rates. Nonlinear forms include a hyperbolic tangent function for the on-rate, representing a faster-than-linear increase for intermediate shear rates, and an exponential relationship for the off-rate, reflecting reduced bond lifetimes as shear increases.

doi: https://doi.org/10.1371/journal.pcbi.1014241.g004