VUStruct: A compute pipeline for high throughput and personalized structural biology
Fig 3
Screenshot of the VUStruct-generated transcript variant report, showing the variant location as a pink diamond in the context of the protein’s PFAM domain [53] annotation.
This is followed by results for Rate4Site, COSMIS, MusiteDeep, and ScanNet calculations. A key table is the Structure Summary, which lists all the structures (from the PDB, MODBASE, SWISS-MODEL database, and AlphaFold database) on which calculations were performed. For example, the highlighted row summarizes all the calculations performed on X-Ray crystal structure 1a6b.pdb, and the highlighted shortcut in the left column leads to the section of the page detailing those results (see next Fig).