VUStruct: A compute pipeline for high throughput and personalized structural biology
Fig 2
Screenshot from the VUStruct-generated case report landing web page.
In the table, each row summarizes the range of calculated values for each variant. Ranges arise in some calculations because multiple structures are considered for each transcript. In the case of input genomic coordinates, multiple transcript isoforms are often impacted for each variant. The “Refresh Cluster Jobs Information” box allows detailed monitoring and troubleshooting. The drawn red box shows how summary row 14 (a change to gene HFE on Chrom 6) has been expanded to display five rows for different impacted transcripts. The first row corresponds to the canonical UniProt isoform. Clicking the “Report” link for that line will display detailed calculations for this variant in the context of that transcript (see next Fig).