Deciphering the cardiac neuron landscape in heart failure patients
Fig 7
Construction of a predictive model for heart failure using N4-ALK associated features.
(a) Identification of co-expressed gene modules within neurons. (b) The scores of four gene modules in ten subsets of neurons. (c) Overlapping genes of “yellow” module and genes detected in data sets GSE141910, GSE165303, GSE145154, and GSE57345. (d) Heat map displaying the AUC score of each heart failure prediction model, and bar plot illustrating its average AUC score across four datasets. (e) The differential enrichment scores of 66 genes between the heart failure group and the healthy group in GSE141910 and GSE145154, respectively. Wilcoxon rank-sum test was used. AUC, area under the ROC curve.