Deciphering the cardiac neuron landscape in heart failure patients
Fig 6
Analysis of the molecular mechanism mediated by the newly generated neuronal subsets.
(a) Label transfer learning analysis on the newly generated neuronal map included different etiologies. (b) Differences of the proportion in neuronal subsets across different datasets. (c) The differential expression of PTPRZ1 and ALK between normal heart and diseased heart induced by various etiologies. Wilcoxon rank-sum test was used. (d) Cell-cell communications of PTN signaling pathway. (e) Pairs of ligand and receptor in the interactions between fibroblasts and neurons in the failing heart.