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Unveiling gene perturbation effects through gene regulatory networks inference from single-cell transcriptomic data

Table 5

Spearman correlation (mean ± SEM) between simulated and experimental KO–WT differences for the ten GRNs with lowest CMD or highest FCI. P-values are from one-sided t-tests against zero, with FDR correction across the four KO conditions. Significant results are marked with stars (* p < 0.05, ** p < 0.01, *** p < 0.001).

Table 5

doi: https://doi.org/10.1371/journal.pcbi.1014067.t005