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Unveiling gene perturbation effects through gene regulatory networks inference from single-cell transcriptomic data

Table 1

Comparison of different computational methods for GRN inference, highlighting their input data type, requirement of prior information, capabilities of generating new data, implementation of multiple gene knockouts (KO) simulations, and ability to infer directed interactions. An asterisk (*) indicates that the feature is theoretically supported by the method but was not implemented and discussed in the referenced publication.

Table 1

doi: https://doi.org/10.1371/journal.pcbi.1014067.t001