Unveiling gene perturbation effects through gene regulatory networks inference from single-cell transcriptomic data
Fig 5
Comparison of CMD and FCI selection criteria in mouse GRN inference.
A. Relationship between the fraction of correctly inferred interactions (FCI) and the Correlation Matrices Distance (CMD) for the 250 GRNs inferred with IGNITE from the input dataset (log-normalized scRNA-seq with PST and MB). Each point is a GRN, and it corresponds to a specific set of hyperparameters. The 10 models with the lowest CMD are highlighted in red, and the 10 with the highest FCI in orange.