Putting BASIL in a BLT: A Bayesian filtering method for estimating the fitness effects of nascent adaptive mutations
Fig 7
Histograms of the measured distributions of fitness effects (mDFEs) of adapted lineages inferred by BASIL in nine BLT experiments.
Each panel shows a BLT experiment, as indicated. Gray lines are different replicates. In the top right corner, we provide a short-hand description of the strain (haploids are denoted HYi, diploids are denoted by DY) and environment used in each experiment. “C” and “N” refer to the likely limiting nutrient in the medium, -xd indicates the number days in the growth and dilution cycle, and “+Cr” indicates the presence of the alga Chlamydomonas reinhardtii in the evolution environment (see Tab C in S1 Data for additional details). Thick yellow line shows the mDFE of HY0 in C-2d (Levy 2015, Replicate 1) as reference.