Dual-channel graph learning reveals similarity and complementarity in protein-protein interaction networks
Fig 4
Protein–protein interaction (PPI) examples that are correctly predicted by DMG-PPI but not by HIGH-PPI or TUnA.
The corresponding PPI complex structures are predicted using GRAMM and visualized with ChimeraX. (A) O15264 (Mitogen-activated protein kinase 13) and P51452 (Dual specificity protein phosphatase 3); (B) P11233 (Ras-related protein Ral-A) and Q15208 (Serine/threonine-protein kinase 38); (C) P11597 (Cholesteryl ester transfer protein) and P02647 (Apolipoprotein A-I); (D) P01033 (Metalloproteinase inhibitor 1) and Q9H306 (Matrix metalloproteinase-27).