Deep learning models to map osteocyte networks from confocal microscopy can successfully distinguish between young and aged bone
Fig 5
Deep learning model predicts changes in osteocyte network parameters due to age with similar accuracy to measurements performed manually.
Direct comparison of measurements of percentage decrease in (A) osteocyte density and (B) osteocyte network connectivity as calculated manually by us previously [19], and by our deep learning model. Very similar decreases in osteocyte density were measured (38.03% vs. 34.44%, respectively) while a trend of similar results were found in connectivity of the osteocyte network (43.3% vs. 55.57%, respectively).