SpaConTDS: A multimodal contrastive learning framework for identifying spatial domains by applying tuple disturbing strategy
Fig 4
SpaConTDS achieves superior clustering performance on breast cancer 10x Xenium data.
(A) H&E stained image with manually annotated regions and clustering result with DB index of SpaConTDS on 10x Xenium breast cancer dataset. (B) Violin plots of expression of DEGs (SERPINA3, PTN) in subcluster 4 and 11 versus other clusters. (C) Raw(top) and denoised(bottom) gene expression patterns of PTN. (D) Clustering results with DB index of STAGATE, ConST, GraphST, Scanpy and IRIS.