Decoding the role of DNA sequence on protein-DNA co-condensation
Fig 3
Average interfacial DNA affinity dictates capillary forces.
A and B Capillary force is plotted as a function of at
=84.50
and as a function of
at
=0.6 for homogeneous (salmon) and heterogeneous DNA I (purple), respectively. Each point in the plots represents the average of five independent replicates, with error bars denoting the standard deviation. The snapshots show condensates for heterogeneous DNA I where red represents high-affinity monomers while yellow represents low-affinity monomers. Proteins are shown in green. Snapshots (left to right) show condensates for the following parameter sets: (i)
= 0.2 and
= 84.50
, (ii)
= 0.8 and
= 84.50
, (iii)
= 0.6 and
= 42.25
and (iv)
= 0.6 and
= 126.75
.