Lysergic acid diethylamide-derived excitatory/inhibitory ratio change enhances global synchrony in functional brain dynamics
Fig 5
Probability of occurrence, dwell time, and transition probabilities between 6 PL states.
(A) The first row shows the transition probabilities of the 6 PL states under LSD and placebo conditions, while the second row displays the dwell time. PL states marked with asterisks indicate significant differences assessed by permutation tests, with one asterisk representing FDR uncorrected p < 0.05 and two asterisks representing p < 0.05/k, where k = 6. (B) The matrix of transition probability for PL states under LSD and placebo conditions. Compared to the placebo condition, all probabilities of transitioning out of PL state 3 decreased under LSD (highlighted in the blue box), while all probabilities of transitioning into PL state 3 increased (highlighted in the red box), with significant changes indicated by asterisks. (C) Changes in transition probabilities between PL states under LSD compared to the placebo condition. Red/blue arrows indicate higher/lower transition probabilities in the LSD condition compared to the placebo condition, with significant differences marked by asterisks.