Lysergic acid diethylamide-derived excitatory/inhibitory ratio change enhances global synchrony in functional brain dynamics
Fig 3
Repertoire of spatially distributed phase-locking patterns (PL states) obtained using the Leading Eigenvector Dynamics Analysis (LEiDA).
Each column corresponds to a distinct brain state. (A) The bar plot showing the cluster centroid vectors (i.e., PL states), where each element of the centroid vector Vc represents the projection of the BOLD phase of each region onto Vc. If the BOLD phase of a region aligns with the direction of Vc, the corresponding element is positive (colored red); otherwise, it is negative (colored blue). (B) The representation of brain regions based on their contributions, where the magnitude of each element in Vc indicates the contribution of that brain region to the respective PL state, with color intensity reflecting the value. (C) The PL states are represented in matrix format by computing the outer product of Vc × VcT, as depicted in the bottom panel.