DDGWizard: Integration of feature calculation resources for analysis and prediction of changes in protein thermostability upon point mutations
Fig 7
Prediction results of DDGWizard’s model from the cross-validation.
A: The scatter plot to visualize the comparison between all predicted and true values. The red line indicates the overall regression fit. The plot also provides the regression equation, R2, γ, and σ values for the overall prediction. B: The binned scatter plot compares average prediction values and experimental values within 10 bins that have equivalent data amounts. The error bars represent the standard error of the residuals between the average predicted and true values within each bin. C: The scatter plot to visualize the prediction results from the 20-fold cross-validation on the 3,970 mutation Î"Î"G data points where the PSSM score of the mutant amino acid is less than 0. D: The scatter plot to visualize the prediction results from the 20-fold protein-level crossvalidation on the 30 proteins that have mutual sequence similarity less than 30%.