Skip to main content
Advertisement

< Back to Article

Ohno-miRNAs: miRNA pairs derived from whole-genome duplication

Fig 3

Comparative analysis of regulatory motifs among WGD and SSD miRNA pairs.

V-Motif (A1-A2), Bifan (B1-B2), PPI-Bifan (C1-C2), and PPI-Delta (D1-D2). Panels A1-D1 show the distribution of enrichment scores computed for each miRNA-target pair (WGD pairs on the left, SSD pairs on the right). Panels A2-D2 display the number of motif instances collected in classes: For V-motifs (A2), pairs are binned by the number of motifs (0, 1–50, >50); for all other motifs (B2, C2, D2), pairs (or single miRNAs in D2) are separated in two classes, corresponding to being involved in 0 or motif. An enrichment signal relative to WGD pairs is observed for V-Motifs, Bifan, and PPI-Bifan. In contrast, PPI-Delta motifs show minimal differences, with nearly all miRNAs showing no enrichment.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1013766.g003