PyFibers: An open-source NEURON-Python package to simulate responses of model nerve fibers to electrical stimulation
Fig 8
Modeling of rat vagus nerve stimulation and recording of single fiber action potentials and compound nerve action potentials using the Peña model in ASCENT with PyFibers.
A) Geometrical model instrumented with stimulation (two contacts) and recording (three contacts) cuffs. The cross sectional x-y view does not show the surrounding tissue. The perineurium is modeled using a contact impedance [47] and therefore is not visible as a distinct geometry. B) Single fiber action potentials from select fiber diameters. All fibers were along the nerve centroid. C) Compound action potential resulting from activation of all 14 fibers, calculated as summation of their single fiber action potentials.