Automated and modular protein binder design with BinderFlow
Fig 2
The BFmonitor web-based dashboard.
BFmonitor provides three tools to follow a design campaign in real. (A) A scatter plot that updates in real time, providing information about any two of the variables calculated by scoring.sh. Each data point corresponds to an individual binder, and only those that fulfil all in silico criteria get colored. (B) A radar plot enables pairwise comparison of all scores calculated for any two binders, providing visual information on how each metric compares between the two candidates. (C) An interactive 3D viewer allows to inspect the backbones of in silico hits (yellow cartoon) interactively in the context of the target protein (grey surface) in real time.