Integrative multi-omics framework for causal gene discovery in Long COVID
Fig 6
Cluster-level heat-map of the 32 candidate Long-COVID genes.
The heat-map shows the mean gene expression for each cluster, highlighting distinct expression patterns across the three patient groups. Hierarchical clustering of genes (shown at top) reveals coordinated expression patterns. The color gradient represents z-scored log2 expression values (viridis color scale: dark-purple = low expression, bright-yellow = high expression), demonstrating cluster-specific gene signatures associated with different Long COVID phenotypes. A sample-level heat-map showing individual subject gene expression is available in S5 Table and S2 Fig.